Presentation

The Genomics and Biomedicine research group (GXB) at the University of Vigo is a multidisciplinary team equipped to tackle ambitious new challenges in biomedical and genomic research.

GXB is currently coordinated by David Posada and includes principal investigators Diana Valverde, Carmen Rodríguez, Miguel Arenas, Iria Fernández-Silva, and María Mayán, along with multiple postdoctoral researchers, graduate students, and technical staff.

Our group is part of the Center for Nanomaterials and Biomedicine (CINBIO) at the University of Vigo, a Singular Research Center recognized by the Galician Government.

Our research is funded by the University of Vigo, the Consellería de Cultura, Educación e Ordenación Universitaria of the Galician Government, the Ministerio de Ciencia, Innovación y Universidades of the Spanish Government, and the European Union.

Research

The Genomics and Biomedicine Group (GXB) carries out its research in three areas: genomics of diseases and pathogens, molecular biology applied to biomedicine, and nanomaterials in biomedicine.

In the area of genomics of diseases and pathogens, the GXB studies cancer genomics through single-cell analysis and liquid biopsy, the molecular evolution of human pathogenic viruses such as HIV-1, SARS-CoV-2, and CCHFV, including resistance to antiretrovirals, and evolutionary genomics applied to the conservation of biological resources, with European and national funding and collaborations with Galician hospitals.

In the area of molecular biology applied to biomedicine, research focuses on the genetic basis of rare ciliary diseases and pulmonary arterial hypertension, supported by ISCIII-FIS, as well as on the mechanisms of aging in cancer and osteoarthritis, seeking new therapeutic targets and biomarkers.

In the area of nanomaterials for biomedicine, GXB designs green-chemistry nanomaterials with antitumor and antimicrobial applications and develops drug-delivery systems and mRNA therapies against cancer.

People

Principal investigators

Postdoctoral researchers

  • Joao Alves (mail)
  • Nuria Estévez (mail)
  • Noelia González-Ballesteros (mail)
  • Loretta de Chiara (mail)
  • Valeria Zoni (mail)
  • Carlos López-Solarat (mail)
  • Laura Tomás (mail)
  • Kylie Chen (mail)
  • Luis Daniel González (mail)
  • Adrián Cordido (mail)

PhD students

  • Sarai Moledo (mail)
  • Laura Ceide (mail)
  • Alfonso Bravo (mail)
  • Sara Vila (mail)
  • Elena Pazos (mail)
  • Paula Iglesias (mail)
  • Alexander Carneiro (mail)
  • Iñaki López (mail)
  • Rebeca Martínez (mail)
  • Anxo Nogueira (mail)
  • Ana Fernández
  • Cristian Alvela

Staff

  • Merchi Rodríguez (mail)
  • Francesco di Martino (mail)
  • Soumadipta Mazumdar (mail)
  • Agatha Carretero

Contact

Our labs can be found in three close locations at the As Lagoas-Marcosende campus of the University of Vigo:

  • School of Biology
    • Diana Valverde
  • School of Chemistry
    • Carmen Rodríguez-Argüelles
  • CINBIO
    • David Posada
    • Miguel Arenas
    • Iria Fernández-Silva
    • María Mayán

Phone: (+34) 986 130050
Email: xb5lab@gmail.com

News

New paper on Materials Today Nano

Our new study, published in Materials Today Nano as part of the European PERSEUS project, explores a sustainable approach to photodynamic cancer therapy using hypericin-synthesized metal nanoparticles. Silver nanoparticles enhanced light-induced cancer cell killing in both 2D cultures and 3D tumor spheroids, highlighting their potential for developing new cancer treatment strategies. Read the full article …

Xunta de Galicia continues to support our group

We are proud to announce that the Xunta de Galicia continues to support the Genomics and Biomedicine Group (GXB) at the University of Vigo as a Competitive Reference Group within the Center for Biomedical Research (CINBIO), a Singular Research Center recognized by the Galician Government. This continued support enables us to advance our research in …