We’ve just secured funding from the Spanish Ministry of Science for our project: “Genomic and Transcriptomic Drivers of Adaptation in Cancer Evolution.” Cancer cells can develop traits such as rapid growth, immune evasion, and drug resistance—not only through DNA mutations but also by altering gene expression. Using single‑cell DNA and RNA sequencing, we’re exploring how tumor cell lineages adapt to new environments, focusing on papillary thyroid and colorectal cancers. Our goal: uncover how phenotypic plasticity and heritable changes fuel cancer progression, paving the way for better diagnosis and therapy