María Mayán, a CINBIO researcher, and her team of PhD and postdoctoral students have joined the GXB group. We are very happy about this incorporation. We will update the web as soon as possible!
We are hiring a lab tech!
We are looking for a full-time laboratory technician. Offer 1023-109593 (in Spanish and English) at https://secretaria.uvigo.gal/uv/web/convocatoria/public/show/1150. Open until June 6. Let’s work together!
phylogenetic origins of relapse using single-cell data
Our phylogenetic analysis of single cells exposes how, where and when malignant cells survive treatment in a personalized manner in a liver relapse of a CRC metastasis. We show that the relapse originated from the expansion of a single metastatic lineage that slowly evolved in the liver. Interestingly, there is a clear contribution of chemotherapy exposure to the overall mutational burden of the relapse
https://www.sciencedirect.com/science/article/pii/S0304383522002518
Understanding SARS-CoV-2 transmission
Together with colleagues at a local hospital, here we show that is not easy to figure out with just genomics who infected whom with SARS-CoV-2
Limited Genomic Reconstruction of SARS-CoV-2 Transmission History Within Local Epidemiological
CellPhy paper
Finally out! ML inference of single-cell phylogenies
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-021-02583-w
Download CellPhy at: https://github.com/amkozlov/cellphy
AECC grant: Microbiome as biomarker for CRC
We want to thank the Spanish Cancer Association (AECC) for awarding us a research grant to study the role of the microbiome (virus and bacteria) as non-invasive biomarkers for the detection of premalignant lesions and colorectal cancer. Anonymous people have donated this money; much gratitude and tons of responsibility.
New Ph.D. fellowships!
Congratulations to Pilar Gallego and Pablo Fonseca for their Xunta de Galicia Ph.D. fellowships! Pilar is already working on SARS-CoV-2 evolution in Galicia, and Pablo is about to start working –together with Monica Martinez at the IISGS– on genomic biomarkers for lung cancer immunotherapy.
Job offer: Technician in molecular and cellular biology, University of Vigo
Description: A position is offered as a molecular and cellular biology laboratory technician to work in the MICINN project (PID2019-106247GB-I00) “Genomic heterogeneity of circulating tumor cells” (IP: David Posada; University of Vigo; http://darwin.uvigo.es).
Working conditions: Initial duration of 6 months with the possibility of an extension, with an annual gross salary of € 15,000 € in 12 payments. Immediate incorporation.
Place of work: The work will be carried out between the Center for Biomedical Research (CINBIO) of the University of Vigo and the Institute for Health Research of Santiago de Compostela (IDIS).
Functions:
- Maintain cell cultures.
- Execute basic experimental techniques with laboratory animals (rodents): anesthesia, analgesia, surgical procedures, etc.
- Extract and process biological samples from laboratory animals.
- Handle human blood samples.
- Extract DNA / RNA.
- Determine the concentration and quality of DNA / RNA samples.
- Organize and store blood, tissue and DNA / RNA samples.
- Maintain the stock and inventory of laboratory reagents.
Profile:
Minimum requirements
- Be in possession of the title of Superior Laboratory Technician (FP): specialty related to Biomedicine. Candidates without this qualification will not be evaluated.
- Be in possession of the qualification of training to perform procedures on laboratory animals and euthanasia (b and c) (in accordance with EU Directive 63/2010, RD 53/2013 and ECC / 566/2015).
- Experience in rodent xenograft modeling, processing and sampling.
- Knowledge of the standards of good laboratory practice (GLP) and of routine and experimental processes with animals.
- Experience in cellular / molecular biology techniques: cell culture, DNA and RNA isolation, PCR and qPCR.
Valuable requirements
- Cell culture experience.
- Experience in isolation of blood cell populations and immunofluorescence techniques.
- Experience in nucleic acid extractions from blood, cells and tumors.
- Demonstrable experience in biomedical research.
- Minimum of 2 years experience in laboratory work.
- English level B2 Common European Framework of Reference for Languages (MCREL) or similar.
Presentation of candidatures:
Interested persons should send their CV and two reference contacts to xb5lab@gmail.com, indicating “lab technician 2021” in the subject of the email, until June 20, 2021.
New Ph.D. thesis in the lab! : Harry Detering
Congratulations to Harry for his Ph.D!
Harald Detering (2021). Computational assessment of methods for inferring intratumoral genomic heterogeneity.
JOB: Bioinformatician in protein modeling (open!)
RESEARCH CONTRACT: Protein Modeling
• Workplace: CME Lab, CINBIO, Universidade de Vigo, Spain. https://cme.webs.uvigo.es
• Duration: 12 months, May (2021) – April (2022), could be extended.
• Gross remuneration: Approx 2,000 euros per month (gross salary), depending on qualifications
TASKS TO BE PERFORMED
• Modeling of proteins (homology modeling, docking protein-ligand, molecular dynamics)
ESSENTIAL REQUIREMENTS
• Experience in protein modeling (homology modeling, docking protein-ligand, molecular dynamics)
• University degree or PhD in Biology, Chemistry, Physics, Biotechnology or similar.
• Programming in basic languages (i.e., Python, R, C)
MERITS TO VALUE
• Experience in protein modeling (homology modeling, docking protein-ligand, molecular dynamics)
• Experience in protein evolution
• Script programming (i.e., Python, R or C) and supercomputing capabilities
• CV (degrees, scientific publications and communications, English, computer programming)
APPLICATION
• Before April 26, 2021
• Those interested must send A single pdf with [cover letter, academic record with qualifications (non-doctors), Bachelor’s degree, Doctor’s degree (doctors), copy of ID card, CV and attachments that the candidate wish to include] to the following address: marenas@uvigo.es, with subject “CONTRACT_MCI_NAMEANDLASTNAMEOFTHECANDIDATE” before April 26, 2021.
For further information contact marenas@uvigo.es
Oferta para contratación de personal de investigación en modelado computacional de proteínas [Noviembre 2020]
Se oferta un contrato de investigador en bioinformática (modelado de proteínas) con cargo a un proyecto asociado al programa Ramón y Cajal (Ministerio de Ciencia e Innovación)
Características del contrato
Duración: 4 meses (enero-abril 2021) a tiempo completo.
Retribución aproximada: 1750 euros brutos / mes
Lugar de trabajo: CINBIO, Universidad de Vigo
Requisitos de los aspirantes
– Titulación: Graduado con Máster o Doctor (preferible), en ciencias experimentales: Biología, Química, Biotecnología, Física o afines.
– Experiencia en:
Bioinformática estructural de modelado de proteínas (modelado por homología, dinámica molecular, docking)
Lenguajes de programación
Análisis de datos e interpretación de resultados
For an English version of this announcement of vacancy please contact Miguel Arenas by email.
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